Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 1.844


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SMARCA1chrX_-_128657381-0.802.0e-04Click!
SMARCA5chr4_+_1444345550.721.5e-03Click!
SMARCC2chr12_-_565833010.581.8e-02Click!
NCOR1chr17_-_159737600.136.4e-01Click!
NCOR2chr12_-_1250520090.136.4e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_29641087 6.160 EVI2B
ecotropic viral integration site 2B
chr12_-_15114495 4.758 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_150738232 4.636 CTSS
cathepsin S
chr2_+_143886969 4.187 ARHGAP15
Rho GTPase activating protein 15
chrX_+_78200828 4.059 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr22_+_23229959 4.050 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr2_+_143886898 4.017 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr19_-_39826676 3.810 NM_004877
GMFG
glia maturation factor, gamma
chr19_-_39826625 3.512 GMFG
glia maturation factor, gamma
chr19_-_17516383 3.462 NM_004335
BST2
bone marrow stromal cell antigen 2
chr1_+_198608216 3.337 PTPRC
protein tyrosine phosphatase, receptor type, C
chr5_-_94417185 3.320 MCTP1
multiple C2 domains, transmembrane 1
chr5_-_149792276 3.191 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_+_44746889 3.180 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr7_+_74188308 3.134 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr5_-_138725544 2.856 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr1_-_150738255 2.815 CTSS
cathepsin S
chr5_-_169724734 2.764 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_+_75988838 2.757 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75988765 2.754 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr17_-_29641068 2.718 EVI2B
ecotropic viral integration site 2B
chr1_-_150738292 2.693 NM_001199739
NM_004079
CTSS

cathepsin S

chr1_+_32739711 2.677 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr17_-_29641094 2.664 NM_006495
EVI2B
ecotropic viral integration site 2B
chr1_+_198608136 2.659 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr15_+_89182038 2.630 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_40198526 2.587 NM_004310
RHOH
ras homolog gene family, member H
chr13_-_46756326 2.468 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_-_169724817 2.389 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_25205180 2.384 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr20_+_44746948 2.372 CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_-_169724782 2.362 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_+_37639246 2.325 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr6_-_32908583 2.312 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr10_-_14372807 2.274 NM_018027
FRMD4A
FERM domain containing 4A
chr5_-_94417544 2.139 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr12_+_25205488 2.082 LRMP
lymphoid-restricted membrane protein
chr22_+_40322609 1.987 GRAP2
GRB2-related adaptor protein 2
chr10_-_11574273 1.976 NM_001080491
USP6NL
USP6 N-terminal like
chr16_+_12058963 1.957 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr6_+_31539875 1.884 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr1_+_948846 1.850 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr6_+_29691116 1.837 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr8_-_102803196 1.824 NCALD
neurocalcin delta
chr5_-_149792370 1.812 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr1_+_32716839 1.800 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr14_-_106691698 1.796


chrX_+_37639306 1.753 CYBB
cytochrome b-245, beta polypeptide
chr1_+_79115476 1.712 NM_006417
IFI44
interferon-induced protein 44
chr12_+_11802905 1.706 ETV6
ets variant 6
chr1_-_151319674 1.703 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr12_-_53601051 1.699 ITGB7
integrin, beta 7
chr14_-_23288912 1.682 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_-_34207308 1.672 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr3_+_121796695 1.649 NM_006889
NM_176892
CD86

CD86 molecule

chr7_-_120498128 1.643 NM_012338
TSPAN12
tetraspanin 12
chrX_-_30595883 1.631 NM_025159
CXorf21
chromosome X open reading frame 21
chr18_-_53071225 1.596 NM_001243232
TCF4
transcription factor 4
chr8_-_102803178 1.563 NCALD
neurocalcin delta
chr16_-_4896197 1.509 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_-_214015053 1.447 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_+_167298280 1.440 NM_001198783
POU2F1
POU class 2 homeobox 1
chr17_+_6659356 1.345 XAF1
XIAP associated factor 1
chr5_-_169724614 1.329 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr8_-_102803438 1.299 NM_032041
NCALD
neurocalcin delta
chr17_-_34417386 1.260 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr18_-_51690988 1.255 MBD2
methyl-CpG binding domain protein 2
chr3_+_119316694 1.249 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr8_+_26150731 1.243 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_+_5646206 1.230 NM_021616
TRIM34
tripartite motif containing 34
chr1_-_9129666 1.201 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr11_+_5710926 1.176 TRIM22
tripartite motif containing 22
chr12_+_11802726 1.156 NM_001987
ETV6
ets variant 6
chr22_+_40297085 1.142 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr1_+_174844655 1.136 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr19_-_48759141 1.116 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr1_+_32666201 1.093 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr4_+_147096834 1.091 NM_007080
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_207095198 1.069 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_+_133118789 1.056 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr1_-_151319717 1.052 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr12_+_11802642 1.024 ETV6
ets variant 6
chr19_-_36233311 1.008 NM_024660
IGFLR1
IGF-like family receptor 1
chr13_-_46756295 0.985 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_9129583 0.970 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr14_+_64680858 0.959 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr1_+_198608244 0.956 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_-_13408368 0.951 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr4_-_38806410 0.948 NM_003263
TLR1
toll-like receptor 1
chr7_-_115670828 0.936 NM_001018058
NM_012252
TFEC

transcription factor EC

chr2_-_191878908 0.933 STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_159175048 0.933 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_+_167298382 0.930 POU2F1
POU class 2 homeobox 1
chr7_-_115670774 0.902 TFEC
transcription factor EC
chr17_-_80407601 0.901 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr17_+_6659155 0.895 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr22_+_40297183 0.890 GRAP2
GRB2-related adaptor protein 2
chr21_+_43919741 0.886 NM_018964
SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr21_-_15918635 0.875 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_-_160472960 0.869 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr3_-_49851217 0.863 UBA7
ubiquitin-like modifier activating enzyme 7
chr3_-_58200397 0.848 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_101185195 0.842 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr6_+_138188352 0.834 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_-_53600999 0.820 NM_000889
ITGB7
integrin, beta 7
chr5_+_162887516 0.803 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr11_+_5710816 0.802 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr2_-_172291227 0.798 NM_024770
METTL8
methyltransferase like 8
chr3_+_187086167 0.793 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr7_+_28452143 0.793 NM_182898
CREB5
cAMP responsive element binding protein 5
chr10_-_99052429 0.791 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr13_-_72440557 0.787 DACH1
dachshund homolog 1 (Drosophila)
chr3_+_63953419 0.786 NM_001128149
ATXN7
ataxin 7
chr14_+_65877309 0.780 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr5_+_102465256 0.780 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr12_-_49319211 0.765 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr17_-_62084282 0.759 NM_000873
ICAM2
intercellular adhesion molecule 2
chr18_-_53303129 0.758 NM_001243226
TCF4
transcription factor 4
chr9_-_5304579 0.757 NM_005059
NM_134441
RLN2

relaxin 2

chr12_-_49318663 0.750 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr2_-_191878882 0.746 STAT1
signal transducer and activator of transcription 1, 91kDa
chr9_+_100174369 0.745 TDRD7
tudor domain containing 7
chr10_+_35426709 0.743 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr13_-_72440143 0.736 DACH1
dachshund homolog 1 (Drosophila)
chr12_+_48513012 0.734 NM_000289
PFKM
phosphofructokinase, muscle
chr11_-_128392061 0.731 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr7_+_119913688 0.725 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr9_-_8733893 0.717 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr11_-_107729523 0.717 SLC35F2
solute carrier family 35, member F2
chr17_-_40264687 0.717 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr4_-_71532206 0.714 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr9_+_128510477 0.713 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr11_-_47545539 0.710 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr20_-_23062786 0.706 CD93
CD93 molecule
chr2_+_172821874 0.699 HAT1
histone acetyltransferase 1
chr1_+_179923870 0.698 NM_014810
CEP350
centrosomal protein 350kDa
chr10_-_123734708 0.695 NM_001167865
NM_017615
NSMCE4A

non-SMC element 4 homolog A (S. cerevisiae)

chr11_-_104905849 0.692 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr14_-_100841793 0.685 WARS
tryptophanyl-tRNA synthetase
chr15_+_74900712 0.684 NM_003992
CLK3
CDC-like kinase 3
chr22_-_23922376 0.682 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr14_+_37126772 0.680 NM_006194
PAX9
paired box 9
chr3_+_151985828 0.667 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr1_-_9129620 0.664 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_107729492 0.662 SLC35F2
solute carrier family 35, member F2
chr6_-_159239254 0.662 EZR
ezrin
chr1_-_47695442 0.661 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr7_-_99698993 0.658 MCM7
minichromosome maintenance complex component 7
chrX_-_135863033 0.648 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_-_26789062 0.647 RNF6
ring finger protein (C3H2C3 type) 6
chr10_-_99052358 0.642 ARHGAP19
Rho GTPase activating protein 19
chr20_-_52199635 0.642 NM_006526
ZNF217
zinc finger protein 217
chr8_+_56792345 0.641 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr19_-_47617008 0.640 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr2_-_163174816 0.635 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr21_+_42792441 0.634 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr18_+_13611664 0.634 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr5_-_88119604 0.632 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr17_-_67311773 0.631 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr14_+_76618244 0.630 NM_017926
NM_017972
C14orf118

chromosome 14 open reading frame 118

chr3_+_48507621 0.630 TREX1
three prime repair exonuclease 1
chr1_+_156119734 0.626 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_-_106725232 0.623 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr8_-_90996785 0.616 NBN
nibrin
chr12_+_123011780 0.613 NM_014708
KNTC1
kinetochore associated 1
chr11_-_64570621 0.612 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr13_-_47470967 0.609 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr6_-_159239198 0.606 EZR
ezrin
chr19_-_50413063 0.604 NUP62
nucleoporin 62kDa
chr5_-_176738831 0.603 MXD3
MAX dimerization protein 3
chr17_-_67138013 0.597 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr1_-_33502484 0.592 NM_001199199
NM_001625
NM_013411
AK2


adenylate kinase 2


chr11_-_89224413 0.580 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr6_+_72596405 0.572 RIMS1
regulating synaptic membrane exocytosis 1
chr7_-_99699030 0.570 MCM7
minichromosome maintenance complex component 7
chr16_+_27438578 0.566 NM_021798
IL21R
interleukin 21 receptor
chr12_+_54447660 0.565 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr10_-_123734641 0.565


chr5_-_142815076 0.564 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr11_+_9596233 0.562 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr1_-_160832466 0.561 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr8_+_56792392 0.554 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_-_17184500 0.550 COPS3
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
chr10_-_123734271 0.548 NSMCE4A
non-SMC element 4 homolog A (S. cerevisiae)
chr16_-_67970651 0.538 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr5_+_32585604 0.538 NM_006713
SUB1
SUB1 homolog (S. cerevisiae)
chr6_-_24719286 0.533 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr6_-_159239269 0.531 NM_003379
EZR
ezrin
chr5_+_118691692 0.529 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_106505876 0.519 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr8_+_17822093 0.519 PCM1
pericentriolar material 1
chr18_-_53089722 0.514 NM_001243233
TCF4
transcription factor 4
chr4_-_169239816 0.513 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr10_-_99052391 0.506 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr16_-_67970734 0.505 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr15_+_42787457 0.503 NM_003825
NM_130798
SNAP23

synaptosomal-associated protein, 23kDa

chr1_-_154832187 0.497 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr21_-_39956823 0.493 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_39017608 0.487 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chrX_-_80457440 0.484 NM_030763
HMGN5
high mobility group nucleosome binding domain 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.36 1.37e-10 GO:0002376 immune system process
6.57 7.56e-09 GO:0006955 immune response
7.45 4.96e-06 GO:0050776 regulation of immune response
10.53 1.20e-05 GO:0045321 leukocyte activation
5.06 5.47e-05 GO:0006952 defense response
11.54 1.68e-04 GO:0051251 positive regulation of lymphocyte activation
10.78 2.85e-04 GO:0002696 positive regulation of leukocyte activation
10.58 3.26e-04 GO:0050867 positive regulation of cell activation
10.52 3.41e-04 GO:0046649 lymphocyte activation
6.39 3.65e-04 GO:0002684 positive regulation of immune system process
10.10 4.64e-04 GO:0019221 cytokine-mediated signaling pathway
4.92 6.15e-04 GO:0002682 regulation of immune system process
12.15 6.78e-04 GO:0050870 positive regulation of T cell activation
9.22 9.29e-04 GO:0051249 regulation of lymphocyte activation
9.12 1.00e-03 GO:0071345 cellular response to cytokine stimulus
11.11 1.24e-03 GO:0009615 response to virus
3.01 1.30e-03 GO:0048583 regulation of response to stimulus
8.39 1.87e-03 GO:0002694 regulation of leukocyte activation
13.20 2.49e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
8.05 2.54e-03 GO:0050865 regulation of cell activation
9.91 2.65e-03 GO:0050863 regulation of T cell activation
12.12 4.09e-03 GO:0042110 T cell activation
6.34 4.41e-03 GO:0045087 innate immune response
5.28 6.73e-03 GO:0001775 cell activation
6.90 7.87e-03 GO:0050778 positive regulation of immune response
15.22 7.99e-03 GO:0050852 T cell receptor signaling pathway
6.57 1.12e-02 GO:0034097 response to cytokine stimulus
9.53 1.62e-02 GO:0002697 regulation of immune effector process
12.35 2.21e-02 GO:0050851 antigen receptor-mediated signaling pathway
11.34 3.32e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.55 3.72e-02 GO:0051707 response to other organism
7.99 4.32e-02 GO:0002764 immune response-regulating signaling pathway

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
22.21 2.20e-02 GO:0042611 MHC protein complex
63.42 2.83e-02 GO:0043020 NADPH oxidase complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
83.23 3.85e-04 GO:0016175 superoxide-generating NADPH oxidase activity
51.22 1.94e-03 GO:0050664 oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor
5.01 3.64e-02 GO:0008047 enzyme activator activity